Conformational dynamics between transmembrane domains and allosteric modulation of a metabotropic glutamate receptor

Metabotropic glutamate receptors (mGluRs) are class C, synaptic G-protein-coupled receptors (GPCRs) that contain large extracellular ligand binding domains (LBDs) and form constitutive dimers. Despite the existence of a detailed picture of inter-LBD conformational dynamics and structural snapshots o...

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書誌詳細

出版年:	eLife
主要な著者:	Vanessa A Gutzeit, Jordana Thibado, Daniel Starer Stor, Zhou Zhou, Scott C Blanchard, Olaf S Andersen, Joshua Levitz
フォーマット:	論文
言語:	英語
出版事項:	eLife Sciences Publications Ltd 2019-06-01
主題:	GPCRs glutamate receptor conformational dynamics
オンライン･アクセス:	https://elifesciences.org/articles/45116