PGI2 as a Regulator of Inflammatory Diseases

Prostacyclin, or PGI2, is an end product derived from the sequential metabolism of arachidonic acid via cyclooxygenase and PGI synthase (PGIS). The receptor for PGI2, IP, can be found on a variety of cell types and signaling through this receptor exhibits broad physiological effects. Historically, P...

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Bibliographic Details
Published in:Mediators of Inflammation
Main Authors: Stacy L. Dorris, R. Stokes Peebles
Format: Article
Language:English
Published: Wiley 2012-01-01
Online Access:http://dx.doi.org/10.1155/2012/926968