1H MRS-based metabolite changes at ventral respiratory control centers of the medulla oblongata following administration of morphine in wild-type and GIRK2 mutant mice

Respiratory depression is the leading cause of death in opioid overdose and is closely associated with the development of tolerance following repeated morphine use. However, the neurochemical adaptations in brainstem regions that regulate breathing, particularly under chronic opioid exposure, remain...

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Bibliographic Details

Published in:	Current Research in Physiology
Main Authors:	Ozra Dehkordi, Stephen Lin, Safia Mohamud, Richard M. Millis, Paul C. Wang
Format:	Article
Language:	English
Published:	Elsevier 2025-01-01
Subjects:	1H MRS Pre-bötzinger Morphine GIRK2 channels
Online Access:	http://www.sciencedirect.com/science/article/pii/S2665944125000094