Metamizole does not affect fracture healing in a murine ischemia model

Metamizole is a commonly used analgesic drug in clinical fracture management, which does not affect the healing process under physiological conditions. However, many fracture patients suffer from co-morbidities resulting in ischemic conditions with impaired bone healing. The effect of metamizole on...

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Bibliographic Details
Published in:Frontiers in Physiology
Main Authors: Christian Schönbeck, Janine Stutz, Sebastian T. Schreiber, Lukas Keller, Chiara Siep, Wolfgang Metzger, Mario Giorgi, Irene Sartini, Tobias Fritz, Tim Pohlemann, Michael D. Menger, Emmanouil Liodakis, Matthias W. Laschke, Marcel Orth
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Subjects:
metamizole
ischemia
fracture healing
bone turnover
angiogenesis
mouse
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2025.1630268/full

Internet

https://www.frontiersin.org/articles/10.3389/fphys.2025.1630268/full

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