High-throughput CRISPR technology: a novel horizon for solid organ transplantation

Organ transplantation is the gold standard therapy for end-stage organ failure. However, the shortage of available grafts and long-term graft dysfunction remain the primary barriers to organ transplantation. Exploring approaches to solve these issues is urgent, and CRISPR/Cas9-based transcriptome ed...

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Bibliographic Details

Published in:	Frontiers in Immunology
Main Authors:	Xiaohan Li, Zhang Chen, Weicong Ye, Jizhang Yu, Xi Zhang, Yuan Li, Yuqing Niu, Shuan Ran, Song Wang, Zilong Luo, Jiulu Zhao, Yanglin Hao, Junjie Zong, Chengkun Xia, Jiahong Xia, Jie Wu
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-01-01
Subjects:	solid organ transplantation CRISPR/Cas9 transcriptome editing CRISPR screening high-throughput
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2023.1295523/full