The Role of IFN-β during the Course of Sepsis Progression and Its Therapeutic Potential

Sepsis is a complex biphasic syndrome characterized by both pro- and anti-inflammatory immune states. Whereas early sepsis mortality is caused by an acute, deleterious pro-inflammatory response, the second sepsis phase is governed by acute immunosuppression, which predisposes patients to long-term r...

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Bibliographic Details

Published in:	Frontiers in Immunology
Main Authors:	Gorjana Rackov, Rahman Shokri, Melchor Álvarez De Mon, Carlos Martínez-A., Dimitrios Balomenos
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2017-05-01
Subjects:	IFN IFN-β sepsis macrophages monocytes immunosuppression
Online Access:	http://journal.frontiersin.org/article/10.3389/fimmu.2017.00493/full