Microtubule depolymerization potentiates alpha-synuclein oligomerization
Parkinson’s disease (PD) is associated with perturbed mitochondria function and alpha-synuclein fibrillization. We evaluated potential mechanistic links between mitochondrial dysfunction and alpha-synuclein aggregation. We studied a PD cytoplasmic hybrid (cybrid) cell line in which platele...
| Published in: | Frontiers in Aging Neuroscience |
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| Main Authors: | , |
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2010-01-01
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| Subjects: | |
| Online Access: | http://journal.frontiersin.org/Journal/10.3389/neuro.24.005.2009/full |