Causal Effect of Higher Glycated Hemoglobin (HbA1c) Levels on Knee Osteoarthritis Risk: A Mendelian Randomization Study

Abstract Introduction The association between diabetes mellitus (DM) and risk of osteoarthritis (OA) is inconsistent based on published observational studies. This study aimed to conduct a two-sample Mendelian randomization (MR) analysis to explore the causal link between glycated hemoglobin (HbA1c)...

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Bibliographic Details

Published in:	Rheumatology and Therapy
Main Authors:	Lirong Chen, Chao Jia, Huiqin Yang
Format:	Article
Language:	English
Published:	Adis, Springer Healthcare 2022-12-01
Subjects:	Osteoarthritis Diabetes mellitus Glycated hemoglobin (HbA1c) Mendelian randomization
Online Access:	https://doi.org/10.1007/s40744-022-00510-4