Dexamethasone promotes durable factor VIII-specific tolerance in hemophilia A mice via thymic mechanisms

The development of inhibitory antibodies to factor VIII is the most serious complication of replacement therapy in hemophilia A. Activation of the innate immune system during exposure to this protein contributes to inhibitor development. However, avoidance of factor VIII exposure during innate immun...

詳細記述

書誌詳細

出版年:	Haematologica
主要な著者:	Maria T. Georgescu, Paul C. Moorehead, Alice S. van Velzen, Kate Nesbitt, Birgit M. Reipert, Katharina N. Steinitz, Maria Schuster, Christine Hough, David Lillicrap
フォーマット:	論文
言語:	英語
出版事項:	Ferrata Storti Foundation 2018-08-01
オンライン･アクセス:	https://haematologica.org/article/view/8562