STING Suppresses Mitochondrial VDAC2 to Govern RCC Growth Independent of Innate Immunity

Abstract STING is an innate immune sensor for immune surveillance of viral/bacterial infection and maintenance of an immune‐friendly microenvironment to prevent tumorigenesis. However, if and how STING exerts innate immunity‐independent function remains elusive. Here, the authors report that STING e...

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Bibliographic Details

Published in:	Advanced Science
Main Authors:	Zhichuan Zhu, Xin Zhou, Hongwei Du, Erica W. Cloer, Jiaming Zhang, Liu Mei, Ying Wang, Xianming Tan, Austin J. Hepperla, Jeremy M. Simon, Jeanette Gowen Cook, Michael B. Major, Gianpietro Dotti, Pengda Liu
Format:	Article
Language:	English
Published:	Wiley 2023-01-01
Subjects:	2‐BP innate immunity‐independent mitochondrial homeostasis mTORC1 STING VDAC2
Online Access:	https://doi.org/10.1002/advs.202203718