Synaptic vesicle protein 2A regulates mossy fiber sprouting in a drug-resistant epilepsy rat model via laminin α5/integrin β1

Drug-resistant epilepsy (DRE) is frequently characterized by pathological mossy fiber sprouting (MFS), which is a defining indicator of aberrant synaptic remodeling within the hippocampus. Despite extensive investigations of the molecular underpinnings of MFS, they remain only partially elucidated....

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Bibliographic Details

Published in:	Brain Research Bulletin
Main Authors:	Yongfei Shi, Yi Xu, Yinlin Hu, Langtao Liu, Chen Li, Siyin Ren, Guofeng Wu, Likun Wang
Format:	Article
Language:	English
Published:	Elsevier 2025-10-01
Subjects:	Drug-resistant epilepsy Integrin β1 Laminin α5 Mossy fiber sprouting Synaptic vesicle protein 2 A
Online Access:	http://www.sciencedirect.com/science/article/pii/S036192302500348X