Design, Synthesis, Biological Evaluation, and In Silico Study of Tetrahydropyridines as Prospective Monoamine Oxidase Inhibitors

Abstract The potentiality of monoamine oxidase (MAO) enzymes to break monoamine neurotransmitters makes them efficacious druggable targets. Molecules having MAO‐A inhibition characteristics are utilized as antidepressants while molecules with MAO‐B inhibition prospective are utilized to treat Parkin...

وصف كامل

التفاصيل البيبلوغرافية

الحاوية / القاعدة:	ChemistryOpen
المؤلفون الرئيسيون:	Dr. Obaid ur Rehman Khan, Dr. Bilal Ahmad Khan, Dr. Syeda Shamila Hamdani, Dr. Saquib Jalil, Dr. Peter A. Sidhom, Dr. Khalid Elfaki Ibrahim, Dr. Tarad Abalkhail, Dr. Jamshed Iqbal, Dr. Hatem Tallima, Prof. Dr. Tamer Shoeib, Prof. Dr. Mahmoud A. A. Ibrahim
التنسيق:	مقال
اللغة:	الإنجليزية
منشور في:	Wiley-VCH 2025-10-01
الموضوعات:	pyridine derivatives monoamine oxidase inhibition spectro-analytical techniques molecular docking
الوصول للمادة أونلاين:	https://doi.org/10.1002/open.202400516