Single fibre cytoarchitecture in ventilator-induced diaphragm dysfunction (VIDD) assessed by quantitative morphometry second harmonic generation imaging: Positive effects of BGP-15 chaperone co-inducer and VBP-15 dissociative corticosteroid treatment

Ventilator-induced diaphragm dysfunction (VIDD) is a common sequela of intensive care unit (ICU) treatment requiring mechanical ventilation (MV) and neuromuscular blockade (NMBA). It is characterised by diaphragm weakness, prolonged respirator weaning and adverse outcomes. Dissociative glucocorticoi...

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Bibliographic Details

Published in:	Frontiers in Physiology
Main Authors:	Sofia Mnuskina, Julian Bauer, Anette Wirth-Hücking, Dominik Schneidereit, Stefanie Nübler, Paul Ritter, Nicola Cacciani, Meishan Li, Lars Larsson, Oliver Friedrich
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-06-01
Subjects:	critical illness diaphragm dysfunction second harmonic generation BGP-15 quantitative morphometry
Online Access:	https://www.frontiersin.org/articles/10.3389/fphys.2023.1207802/full