Impact of Protein Coronas on Lipid Nanoparticle Uptake and Endocytic Pathways in Cells

Lipid nanoparticles (LNPs), widely used in disease diagnosis and drug delivery, face the challenge of being surrounded by biological macromolecules such as proteins upon entering the human body. These molecules compete for binding sites on the nanoparticle surfaces, forming a protein corona. The imp...

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Bibliographic Details
Published in:Molecules
Main Authors: Rui Wang, Jing He, Yuhong Xu, Baowei Peng
Format: Article
Language:English
Published: MDPI AG 2024-10-01
Subjects:
Online Access:https://www.mdpi.com/1420-3049/29/20/4818