PROGNOSTIC IMPACT OF IMMUNOHISTOCHEMICAL P53 EXPRESSION IN BONE MARROW BIOPSY IN HIGHER RISK MDS: A PILOT STUDY

Background and objectives: Mutations of the TP53 gene have an unfavorable prognosis in Myelodysplastic Syndromes (MDS). The product of the TP53gene is the p53 protein. Most of TP53mutations entail the accumulation of the protein in the nucleus of tumor cells. The immunohistochemical (IHC) stainin...

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Bibliographic Details

Published in:	Mediterranean Journal of Hematology and Infectious Diseases
Main Authors:	Alfredo Molteni, Emanuele Ravano, Marta Riva, Michele Nichelatti, Laura Bandiera, Lara Crucitti, Mauro Truini, Roberto Cairoli
Format:	Article
Language:	English
Published:	PAGEPress Publications 2019-02-01
Subjects:	MDS prognosis p53 expression
Online Access:	https://www.mjhid.org/index.php/mjhid/article/view/3638