Temporal tracking of microglial and monocyte single-cell transcriptomics in lethal flavivirus infection

Abstract As the resident parenchymal myeloid population in the central nervous system (CNS), microglia are strategically positioned to respond to neurotropic virus invasion and have been implicated in promoting both disease resolution and progression in the acute and post-infectious phase of virus e...

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Bibliographic Details

Published in:	Acta Neuropathologica Communications
Main Authors:	Alanna G. Spiteri, Claire L. Wishart, Duan Ni, Barney Viengkhou, Laurence Macia, Markus J. Hofer, Nicholas J. C. King
Format:	Article
Language:	English
Published:	BMC 2023-04-01
Subjects:	Microglia Monocyte-derived cells Neuroinflammation Virus-induced encephalitis Microglia depletion CNS infection
Online Access:	https://doi.org/10.1186/s40478-023-01547-4