Exosomes from adipose-derived stem cells regulate M1/M2 macrophage phenotypic polarization to promote bone healing via miR-451a/MIF

Abstract Objectives Bone defects caused by diseases and trauma are usually accompanied by inflammation, and the implantation of biomaterials as a common repair method has also been found to cause inflammatory reactions, which affect bone metabolism and new bone formation. This study investigated whe...

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Bibliographic Details
Published in:Stem Cell Research & Therapy
Main Authors: Rui Li, Dize Li, Huanan Wang, Kaiwen Chen, Si Wang, Jie Xu, Ping Ji
Format: Article
Language:English
Published: BMC 2022-04-01
Subjects:
Exosomes
Adipose-derived stem cells
Macrophages
Bone healing
MiRNA
Online Access:https://doi.org/10.1186/s13287-022-02823-1

Internet

https://doi.org/10.1186/s13287-022-02823-1

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