In-silico analysis predicts disruption of normal angiogenesis as a causative factor in osteoporosis pathogenesis

Abstract Angiogenesis-osteogenesis coupling is critical for proper functioning and maintaining the health of bones. Any disruption in this coupling, associated with aging and disease, might lead to loss of bone mass. Osteoporosis (OP) is a debilitating bone metabolic disorder that affects the microa...

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Bibliographic Details

Published in:	BMC Genomic Data
Main Authors:	Remya James, Koushik Narayan Subramanyam, Febby Payva, Amrisa Pavithra E, Vineeth Kumar TV, Venketesh Sivaramakrishnan, Santhy KS
Format:	Article
Language:	English
Published:	BMC 2024-10-01
Subjects:	Hub genes Osteoporosis Postmenopausal osteoporosis Protein-protein interaction network Reactome KEGG
Online Access:	https://doi.org/10.1186/s12863-024-01269-z