Heat shock protein 70 is associated with replicase complex of Japanese encephalitis virus and positively regulates viral genome replication.

Japanese encephalitis virus (JEV) is a mosquito-borne flavivirus that causes the most prevalent viral encephalitis in Asia. The NS5 protein of JEV is a key component of the viral replicase complex, which plays a crucial role in viral pathogenesis. In this study, tandem affinity purification (TAP) fo...

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Bibliographic Details

Published in:	PLoS ONE
Main Authors:	Jing Ye, Zheng Chen, Bo Zhang, Huan Miao, Ali Zohaib, Qiuping Xu, Huanchun Chen, Shengbo Cao
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2013-01-01
Online Access:	http://europepmc.org/articles/PMC3781048?pdf=render