The Old and the New: Prospects for Non-Integrating Lentiviral Vector Technology

Lentiviral vectors have been developed and used in multiple gene and cell therapy applications. One of their main advantages over other vectors is the ability to integrate the genetic material into the genome of the host. However, this can also be a disadvantage as it may lead to insertional mutagen...

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Bibliographic Details
Published in:Viruses
Main Author: Luis Apolonia
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Subjects:
Online Access:https://www.mdpi.com/1999-4915/12/10/1103