Coumarin-Based Dual Inhibitors of Human Carbonic Anhydrases and Monoamine Oxidases Featuring Amino Acyl and (<i>Pseudo</i>)-Dipeptidyl Appendages: In Vitro and Computational Studies

The involvement of human carbonic anhydrase (hCA) IX/XII in the pathogenesis and progression of many types of cancer is well acknowledged, and more recently human monoamine oxidases (hMAOs) A and B have been found important contributors to tumor development and aggressiveness. With a view of an enzy...

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Bibliographic Details

Published in:	Molecules
Main Authors:	Mariangela Agamennone, Marialuigia Fantacuzzi, Simone Carradori, Anél Petzer, Jacobus P. Petzer, Andrea Angeli, Claudiu T. Supuran, Grazia Luisi
Format:	Article
Language:	English
Published:	MDPI AG 2022-11-01
Subjects:	amino acyl coumarins (<i>pseudo</i>)-dipeptidyl coumarins carbonic anhydrases (CAs) monoamine oxidases (MAOs) molecular docking
Online Access:	https://www.mdpi.com/1420-3049/27/22/7884