Nicotine restores olfactory function by activation of prok2R/Akt/FoxO3a axis in Parkinson’s disease

Abstract Background Olfactory dysfunction occurs frequently in Parkinson’s disease (PD). In this study, we aimed to explore the potential biomarkers and underlying molecular pathways of nicotine for the treatment of olfactory dysfunction in 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine (MPTP)-indu...

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出版年:	Journal of Translational Medicine
主要な著者:	Qinglong Guo, Yi Wang, Liangchen Yu, Liao Guan, Xuefei Ji, Xiaohui Li, Gang Pang, Zhenhua Ren, Lei Ye, Hongwei Cheng
フォーマット:	論文
言語:	英語
出版事項:	BMC 2024-04-01
主題:	Parkinson’s disease Nicotine Olfactory bulb Prok2R/Akt/FoxO3a signaling pathway Apoptosis
オンライン･アクセス:	https://doi.org/10.1186/s12967-024-05171-1