Liquid Biopsy-Multiomics Link Adhesion Pathway Dysregulation to Kidney Injury Severity

Introduction: Severe acute kidney injury (AKI) is strongly associated with the risk of developing chronic kidney disease; however, little is known about the cell type–specific mechanisms driving kidney injury severity. Methods: In this multicenter observational study, we used clinically obtained liq...

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Bibliographic Details

Published in:	Kidney International Reports
Main Authors:	Nanditha Anandakrishnan, Zhengzi Yi, Zeguo Sun, Tong Liu, Jonathan Haydak, Sean Eddy, Pushkala Jayaraman, Stefanie DeFronzo, Aparna Saha, Qian Sun, Dai Yang, Anthony Mendoza, Gohar Mosoyan, Huei Hsun Wen, Jia Fu, Thomas Kehrer, Rajasree Menon, Edgar A. Otto, Bradley Godfrey, Joanna Yang, Mayte Suarez-Farinas, Sean Leffters, Akosua Twumasi, Kristin Meliambro, Alexander W. Charney, Adolfo García-Sastre, Kirk N. Campbell, G. Luca Gusella, John Cijiang He, Lisa Miorin, Girish N. Nadkarni, Juan Wisnivesky, Hong Li, Matthias Kretzler, Steve G. Coca, Lili Chan, Weijia Zhang, Evren U. Azeloglu
Format:	Article
Language:	English
Published:	Elsevier 2025-10-01
Subjects:	AKI COVID-19 kidney organoids machine learning multiomics urine proteomics
Online Access:	http://www.sciencedirect.com/science/article/pii/S2468024925004656