Telomerase Reverse Transcriptase (TERT) is a Therapeutic Target of Oleanane Triterpenoid CDDO-Me in Prostate Cancer

Methyl-2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oate (CDDO-Me) is an synthetic oleanane triterpenoid with strong antiprolifertive and proapoptotic activities in cancer cells. However, the effect of CDDO-Me on human telomerase reverse transcriptase (hTERT) and its telomerase activity in prostate canc...

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Bibliographic Details
Published in:Molecules
Main Authors: Subhash C. Gautam, Dorrah Deeb, Ali S. Arbab, Xiaohua Gao, Yongbo Liu
Format: Article
Language:English
Published: MDPI AG 2012-12-01
Subjects:
CDDO-Me
hTERT
telomerase activity
apoptosis
prostate cancer
Online Access:http://www.mdpi.com/1420-3049/17/12/14795

Internet

http://www.mdpi.com/1420-3049/17/12/14795

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