Innovative inhalable dry powder: nanoparticles loaded with Crizotinib for targeted lung cancer therapy

Abstract Crizotinib is a targeted therapy for metastatic non-small cell lung cancer (NSCLC) that is ALK- or ROS1-positive, as well as for conditions such as ALK-positive anaplastic large cell lymphoma and inflammatory myofibroblastic tumor. However, the associated toxicity poses a significant challe...

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Bibliographic Details
Published in:BMC Cancer
Main Authors: Faiza Naureen, Yasar Shah, Maqsood Ur Rehman, Fazli Nasir Fazli Nasir, Abdul Saboor Pirzada, Jamelah Saleh Al-Otaibi, Maria Daglia, Haroon Khan
Format: Article
Language:English
Published: BMC 2025-10-01
Subjects:
Lung cancer
Crizotinib
Pulmonary delivery
Optimization
Polymeric nanoparticles
Inhalable dry powder
Online Access:https://doi.org/10.1186/s12885-025-15015-w

Internet

https://doi.org/10.1186/s12885-025-15015-w

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