Repurposed drugs in combinations exert additive anti-chikungunya virus activity: an in-vitro study

Abstract Chikungunya virus (CHIKV) infection causes chikungunya, a viral disease that currently has no specific antiviral treatment. Several repurposed drug candidates have been investigated for the treatment of the disease. In order to improve the efficacy of the known drugs, combining drugs for tr...

Full description

Bibliographic Details

Published in:	Virology Journal
Main Authors:	Kusuma Sai Davuluri, Rajnandini Ghanghav, Gunwant Ahire, Mahadeo Kakade, Sarah Cherian, Kalichamy Alagarasu, Deepti Parashar
Format:	Article
Language:	English
Published:	BMC 2024-01-01
Subjects:	Chikungunya virus (CHIKV) Drug repurposing Combination of repurposed drugs Synergistic effect In silico screening In vitro validation
Online Access:	https://doi.org/10.1186/s12985-023-02271-0