Delivery of Sophora flavescens Ait. using a dissolving microneedle enables enhanced psoriasis treatment

Objective: To assess the efficiency of a Sophora flavescens Ait (S. flavescens, Ku Shen)-soluble microneedle (SFA-MN) for improving skin lesion symptoms in mice with psoriasis. Methods: SFA-MNs were prepared using a two-mold molding process with 20% w/v polyvinylpyrrolidone and 15% w/v polyvinyl alc...

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Bibliographic Details

Published in:	Journal of Traditional Chinese Medical Sciences
Main Authors:	Zihan Zhou, Jie Zhang, Yiwen Chen, Bingbing Wang, Ping Hou, Zifan Ding, Luzheng Zhang, Jianlin Wang, Nailiang Yang, Cong Yan
Format:	Article
Language:	English
Published:	Elsevier 2025-04-01
Subjects:	Soluble microneedle Sophora flavescens Ait. Psoriasis Immune regulation Drug delivery
Online Access:	http://www.sciencedirect.com/science/article/pii/S2095754825000122