Molecular Imaging of Pulmonary Tuberculosis in an Ex-Vivo Mouse Model Using Spectral Photon-Counting Computed Tomography and Micro-CT

Assessment of disease burden and drug efficacy is achieved preclinically using high resolution micro computed tomography (CT). However, micro-CT is not applicable to clinical human imaging due to operating at high dose. In addition, the technology differences between micro-CT and standard clinical C...

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Published in:	IEEE Access
Main Authors:	Chiara Lowe, Ana Ortega-Gil, Mahdieh Moghiseh, Nigel G. Anderson, Arrate Munoz-Barrutia, Juan Jose Vaquero, Aamir Y. Raja, Aysouda Matanaghi, Alexander I. Chernoglazov, Theodorus Dapamede, Sikiru A Adebileje, Steven Alexander, Maya R. Amma, Marzieh Anjomrouz, Fatemeh Asghariomabad, Ali Atharifard, James Atlas, Kenzie Baer, Stephen T. Bell, Srinidhi Bheesette, Philip H. Butler, Pierre Carbonez, Claire Chambers, Krishna M. Chapagain, Jennifer A. Clark, Frances Colgan, Jonathan S. Crighton, Shishir Dahal, Jerome Damet, Niels J. A. De Ruiter, Robert M. N. Doesburg, Neryda Duncan, Nooshin Ghodsian, Steven P. Gieseg, Brian P. Goulter, Sam Gurney, Joseph L. Healy, Praveen Kumar Kanithi, Tracy Kirkbride, Stuart P. Lansley, V. B. H. Mandalika, Emmanuel Marfo, David Palmer, Raj K. Panta, Hannah M. Prebble, Peter Renaud, Yann Sayous, Nanette Schleich, Emily Searle, Jereena S. Sheeja, Lieza Vanden Broeke, Vivek V. S., E. Peter Walker, Michael F. Walsh, Manoj Wijesooriya, W Ross Younger, Anthony P. H. Butler
Format:	Article
Language:	English
Published:	IEEE 2021-01-01
Subjects:	High resolution translatable molecular imaging photon-counting spectral CT pulmonary tuberculosis micro-CT
Online Access:	https://ieeexplore.ieee.org/document/9419038/