Molecular Imaging of Pulmonary Tuberculosis in an Ex-Vivo Mouse Model Using Spectral Photon-Counting Computed Tomography and Micro-CT

Assessment of disease burden and drug efficacy is achieved preclinically using high resolution micro computed tomography (CT). However, micro-CT is not applicable to clinical human imaging due to operating at high dose. In addition, the technology differences between micro-CT and standard clinical C...

Full description

Bibliographic Details
Published in:	IEEE Access
Main Authors:	Chiara Lowe, Ana Ortega-Gil, Mahdieh Moghiseh, Nigel G. Anderson, Arrate Munoz-Barrutia, Juan Jose Vaquero, Aamir Y. Raja, Aysouda Matanaghi, Alexander I. Chernoglazov, Theodorus Dapamede, Sikiru A Adebileje, Steven Alexander, Maya R. Amma, Marzieh Anjomrouz, Fatemeh Asghariomabad, Ali Atharifard, James Atlas, Kenzie Baer, Stephen T. Bell, Srinidhi Bheesette, Philip H. Butler, Pierre Carbonez, Claire Chambers, Krishna M. Chapagain, Jennifer A. Clark, Frances Colgan, Jonathan S. Crighton, Shishir Dahal, Jerome Damet, Niels J. A. De Ruiter, Robert M. N. Doesburg, Neryda Duncan, Nooshin Ghodsian, Steven P. Gieseg, Brian P. Goulter, Sam Gurney, Joseph L. Healy, Praveen Kumar Kanithi, Tracy Kirkbride, Stuart P. Lansley, V. B. H. Mandalika, Emmanuel Marfo, David Palmer, Raj K. Panta, Hannah M. Prebble, Peter Renaud, Yann Sayous, Nanette Schleich, Emily Searle, Jereena S. Sheeja, Lieza Vanden Broeke, Vivek V. S., E. Peter Walker, Michael F. Walsh, Manoj Wijesooriya, W Ross Younger, Anthony P. H. Butler
Format:	Article
Language:	English
Published:	IEEE 2021-01-01
Subjects:	High resolution translatable molecular imaging photon-counting spectral CT pulmonary tuberculosis micro-CT
Online Access:	https://ieeexplore.ieee.org/document/9419038/

Similar Items

Needle artifact reduction during interventional CT procedures using a silver filter
by: Carlos A. Reynoso-Mejia, et al.
Published: (2024-03-01)

Delayed diagnosis of lung cancer after missed vertebral metastasis on CT
by: M P H Hawkesford, et al.
Published: (2015-03-01)

Pros and Cons of Dual-Energy CT Systems: “One Does Not Fit All”
by: Ana P. Borges, et al.
Published: (2023-01-01)

Biatrial Volumetric Assessment by Non-ECG-Gated CT Pulmonary Angiography Correlated with Transthoracic Echocardiography in Patients with Normal Diastology
by: Deepa Gopalan, et al.
Published: (2022-11-01)

Estimating Hemodynamic Significant Deformations of Brachiocephalic Arteries Using CT Perfusion
by: Vladimir V. Krylov, et al.
Published: (2023-01-01)

Review article: Thoracic involvement in systemic primary vasculitis: radiological patterns and follow-up
by: G Serra, et al.
Published: (2014-03-01)

No Reproducibility, No Progress: Rethinking CT Benchmarking
by: Dmitry Polevoy, et al.
Published: (2025-10-01)

Scientific letter
by: S M Bennji, et al.
Published: (2022-12-01)

Clinical Low-Dose Photon-Counting CT for the Detection of Urolithiasis: Radiation Dose Reduction Is Possible without Compromising Image Quality
by: Julius Henning Niehoff, et al.
Published: (2023-01-01)

Clinical Low Dose Photon Counting CT for the Detection of Urolithiasis: Evaluation of Image Quality and Radiation Dose
by: Julius Henning Niehoff, et al.
Published: (2022-06-01)

Painless lump over the forehead which turned painful: an unusual presentation of hepatocellular carcinoma
by: S P Susheela, et al.
Published: (2015-05-01)

Complex neuroimaging of traumatic brain injury: radiography and computed tomography
by: Anton V. Yarikov, et al.
Published: (2020-10-01)

Comparison of Turbo Flash and dual-energy modes of third-generation dual-source CT in pre-transplant renal angiography: a prospective observational study
by: Navya Christopher, et al.
Published: (2022-08-01)

Condições de radiação em tomografia computadorizada (TC): determinação e calibração de dosímetros
by: Lúcio Chagas Andrade, et al.
Published: (2017-11-01)

RETRACTED ARTICLE: CT, MRI, and 18F-FDG PET/CT imaging features of seven cases of adult pancreatoblastoma
by: Mengnan Wu, et al.
Published: (2022-12-01)

Peritoneal deposits: PET/CT the keen observer
by: Nora Nabil Abdou Ahmed Mikawy, et al.
Published: (2023-05-01)

Ground glass pulmonary nodules: their significance in oncology patients and the role of computer tomography and 18F–fluorodeoxyglucose positron emission tomography
by: Laura Evangelista, et al.
Published: (2018-02-01)

Spectral CT: Current Liver Applications
by: Ana P. Borges, et al.
Published: (2023-05-01)

CASE REPORT OF METASTATIC MELANOMA LESION AFFECTING AN EXTENSIVE AREA OF THE LEFT LOWER LIMB ON 18F-PSMA PET/CT AND 18F-FDG PET/CT IMAGES – INTENDING TO COMPARE THE DISTRIBUTION OF BOTH RADIOTRACERS IN THIS CANCER
by: LARISSA MANSANO DE SOUZA, et al.
Published: (2025-05-01)

Application of micro‐CT to resolve textural properties and assess primary sedimentary structures of deep‐marine sandstones
by: P. H. Cornard, et al.
Published: (2024-11-01)

Application and Evaluation of Spiral CT in the Diagnosis of Congenital Heart Disease in Children
by: Chen W, et al.
Published: (2025-04-01)

Photon-Counting Computed Tomography (PCCT): Technical Background and Cardio-Vascular Applications
by: Antonella Meloni, et al.
Published: (2023-02-01)

Pulmonary embolism in COVID-19: Ventilation and perfusion computed tomography
by: Anna Maria Ierardi, et al.
Published: (2020-01-01)

Para duodenal hernia
by: V Mathur, et al.
Published: (2006-08-01)

Case report : Xanthogranulomatous pyelonephritis - an unusual variety
by: RD Dani, et al.
Published: (2005-04-01)

Limited additional value of dual-layer spectral 4DCT compared with conventional 4DCT for preoperative localization in primary hyperparathyroidism
by: Jorian P. Krol, et al.
Published: (2025-12-01)

Four-Dimensional Dual-Energy Computed Tomography-Derived Parameters and Their Correlation with Thyroid Gland Functional Status
by: Max H. M. C. Scheepers, et al.
Published: (2025-02-01)

Detection of Lung Nodules in Micro-CT Imaging Using Deep Learning
by: Matthew D. Holbrook, et al.
Published: (2021-08-01)

Is Tissue Still the Issue? The Promise of Liquid Biopsy in Uveal Melanoma
by: Daniël P. de Bruyn, et al.
Published: (2022-02-01)

Role of positron-emission tomography/computed tomography (PET/CT) in breast cancer
by: Mohamed Shawky, et al.
Published: (2020-07-01)

On the Embryonic Development of the Nasal Turbinals and Their Homology in Bats
by: Kai Ito, et al.
Published: (2021-03-01)

A high-throughput 3D X-ray histology facility for biomedical research and preclinical applications [version 2; peer review: 3 approved, 1 approved with reservations]
by: Philip J. Basford, et al.
Published: (2023-12-01)

A high-throughput 3D X-ray histology facility for biomedical research and preclinical applications [version 1; peer review: 2 approved]
by: Philip J. Basford, et al.
Published: (2023-08-01)

The e-STROKE Study: The Design of a Prospective Observational Multicentral Study
by: Kateřina Dvorníková, et al.
Published: (2025-01-01)

Is There Still a Role for Two-Phase Contrast-Enhanced CT and Virtual Monoenergetic Images in the Era of Photon-Counting Detector CT?
by: Arne Estler, et al.
Published: (2023-04-01)

Additively manufactured test phantoms for mimicking soft tissue radiation attenuation in CBCT using Polyjet technology
by: Sepideh Hatamikia, et al.
Published: (2023-05-01)

Feasibility of a method for low contrast CT image quality assessment using difference detail curves for abdominal scans
by: Christian Sommer, et al.
Published: (2022-05-01)

Course of Early Neurologic Symptom Severity after Endovascular Treatment of Anterior Circulation Large Vessel Occlusion Stroke: Association with Baseline Multiparametric CT Imaging and Clinical Parameters
by: Matthias Philipp Fabritius, et al.
Published: (2021-07-01)

Investigation of the relationship of CO-RADS and CT patterns with laboratory parameters in COVID-19 patients and a new perspective on the total CT scoring system
by: Nevin Aydin, et al.
Published: (2022-07-01)

Simulation-Based Development of Internet of Cyber-Things Using DEVS
by: Laurent Capocchi, et al.
Published: (2025-06-01)