Oviductal estrogen receptor α signaling prevents protease-mediated embryo death

Development of uterine endometrial receptivity for implantation is orchestrated by cyclic steroid hormone-mediated signals. It is unknown if these signals are necessary for oviduct function in supporting fertilization and preimplantation development. Here we show that conditional knockout (cKO) mice...

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Bibliographic Details

Published in:	eLife
Main Authors:	Wipawee Winuthayanon, Miranda L Bernhardt, Elizabeth Padilla-Banks, Page H Myers, Matthew L Edin, Fred B Lih, Sylvia C Hewitt, Kenneth S Korach, Carmen J Williams
Format:	Article
Language:	English
Published:	eLife Sciences Publications Ltd 2015-12-01
Subjects:	oviduct estrogen receptor preimplantation embryo fertilization innate immunity
Online Access:	https://elifesciences.org/articles/10453