The antagonism of 6-shogaol in high-glucose-activated NLRP3 inflammasome and consequent calcification of human artery smooth muscle cells

Abstract Background Vascular calcification is the major reason for high mortality of cardiovascular complications for diabetes. Interleukin (IL)-1β has been implicated in this pathogenesis, but its precise role and clinical evidence have not been clearly identified. Hence, this study was aimed to in...

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Bibliographic Details
Published in:Cell & Bioscience
Main Authors: Te-Chuan Chen, Chia-Kung Yen, Ying-Chen Lu, Chung-Sheng Shi, Rong-Ze Hsieh, Shun-Fu Chang, Cheng-Nan Chen
Format: Article
Language:English
Published: BMC 2020-01-01
Subjects:
6-Shogaol
Interleukin-1β
NLRP3 Inflammasome
Vascular calcification
Smooth muscle cells
Online Access:https://doi.org/10.1186/s13578-019-0372-1

Internet

https://doi.org/10.1186/s13578-019-0372-1

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