Dopamine D2 receptor-mediated epidermal growth factor receptor signaling regulates neurogenesis in the subventricular zone of adult brain

Mechanisms underlying selective dopaminergic neuronal degeneration in Parkinson's disease (PD) remain unclear. Impaired adult neurogenesis has been implicated in PD pathology, but its molecular regulation is not fully understood. We previously reported that dopamine D2 receptor (D2R)-mediated e...

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Bibliographic Details

Published in:	Neurobiology of Disease
Main Authors:	Yea Jue Kim, Byeong Jun Kang, Jihee Seo, Sion Kim, Eun-chang Lee, Ha-yeon Cho, Donghoon Kim, Im Joo Rhyu, Ja-Hyun Baik
Format:	Article
Language:	English
Published:	Elsevier 2025-08-01
Subjects:	Dopamine D2 receptor Epidermal growth factor receptor Subventricular zone Adult neurogenesis Parkinson's disease Neurodegenerative disorder
Online Access:	http://www.sciencedirect.com/science/article/pii/S0969996125001950