Formulation and Evaluation of Prednisolone Sodium Metazoate-Loaded Mucoadhesive Quatsomal Gel for Local Treatment of Recurrent Aphthous Ulcers: Optimization, In Vitro, Ex Vivo, and In Vivo Studies

This study aims to formulate a buccal mucoadhesive gel containing prednisolone sodium metazoate-loaded quatsomes for efficient localized therapy of recurrent aphthous ulcers. Quatsomes were prepared using a varied concentration of quaternary ammonium surfactants (QAS) and cholesterol (CHO). A 2<s...

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Bibliographic Details

Published in:	Pharmaceutics
Main Authors:	Ashraf Kassem, Hanan Refai, Mohamed A. El-Nabarawi, Menna M. Abdellatif
Format:	Article
Language:	English
Published:	MDPI AG 2023-07-01
Subjects:	recurrent aphthous ulcer buccal mucoadhesive gel quatsomes prednisolone sodium metazoate
Online Access:	https://www.mdpi.com/1999-4923/15/7/1947