Antiplatelet activity of deferiprone through cyclooxygenase-1 inhibition

Thalassemia patients are susceptible to both iron overload and thromboembolism. Deferiprone is an iron chelator that shows an antiplatelet activity and thus may alleviate platelet hyperactivation in thalassemia. Therefore, this study aimed to characterize the inhibitory effects and mechanisms of def...

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Bibliographic Details

Published in:	Platelets
Main Authors:	Ngan Thi Tran, Benjaporn Akkawat, Noppawan Phumala Morales, Ponlapat Rojnuckarin, Rataya Luechapudiporn
Format:	Article
Language:	English
Published:	Taylor & Francis Group 2020-05-01
Subjects:	adp antiplatelet arachidonic acid camp cox-1 deferiprone
Online Access:	http://dx.doi.org/10.1080/09537104.2019.1648782