Staphylococcus aureus persistence in osteocytes: weathering the storm of antibiotics and autophagy/xenophagy

Staphylococcus aureus is a major causative pathogen of osteomyelitis. Intracellular infections of resident bone cells including osteocytes can persist despite gold-standard clinical intervention. The mechanisms by which intracellular S. aureus evades antibiotic therapy are unknown. In this study, we...

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Bibliographic Details

Published in:	Frontiers in Cellular and Infection Microbiology
Main Authors:	Nicholas J. Gunn, Stephen P. Kidd, Lucian B. Solomon, Dongqing Yang, Eugene Roscioli, Gerald J. Atkins
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-06-01
Subjects:	antibiotic autophagy host-pathogen osteocyte rifampicin vancomycin Staphylococcus aureus
Online Access:	https://www.frontiersin.org/articles/10.3389/fcimb.2024.1403289/full