TGF-β: A novel predictor and target for anti-PD-1/PD-L1 therapy

Transforming growth factor-β (TGF-β) signaling regulates multiple physiological processes, such as cell proliferation, differentiation, immune homeostasis, and wound healing. Besides, TGF-β plays a vital role in diseases, including cancer. Accumulating evidence indicates that TGF-β controls the comp...

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Bibliographic Details
Published in:Frontiers in Immunology
Main Authors: Ming Yi, Tianye Li, Mengke Niu, Yuze Wu, Zhenyu Zhao, Kongming Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Subjects:
cancer biotherapy
cancer immunotherapy
tumor microenvironment
TGF-β
PD-1
PD-L1
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1061394/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.1061394/full

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