IL-33-primed human mast cells drive IL-9 production by CD4+ effector T cells in an OX40L-dependent manner

Interleukin-33 (IL-33) is an alarmin released by epithelial cells in response to tissue damage. It activates resident immune sentinel cells, which then produce signals commonly associated with type 2 immune responses, particularly affecting infiltrating antigen-specific T cells. Given that mast cell...

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Bibliographic Details

Published in:	Frontiers in Immunology
Main Authors:	Louise Battut, Edouard Leveque, Salvatore Valitutti, Nicolas Cenac, Gilles Dietrich, Eric Espinosa
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-10-01
Subjects:	mast cell IL-33 OX40L Th cell IL-9
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2024.1470546/full