Integrative model of genomic factors for determining binding site selection by estrogen receptor‐α

Abstract A major question in transcription factor (TF) biology is why a TF binds to only a small fraction of motif eligible binding sites in the genome. Using the estrogen receptor‐α as a model system, we sought to explicitly define parameters that determine TF‐binding site selection. By examining 1...

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Bibliographic Details

Published in:	Molecular Systems Biology
Main Authors:	Roy Joseph, Yuriy L Orlov, Mikael Huss, Wenjie Sun, Say Li Kong, Leena Ukil, You Fu Pan, Guoliang Li, Michael Lim, Jane S Thomsen, Yijun Ruan, Neil D Clarke, Shyam Prabhakar, Edwin Cheung, Edison T Liu
Format:	Article
Language:	English
Published:	Springer Nature 2010-12-01
Subjects:	chromatin DNA binding modeling recognition motifs transcription factor
Online Access:	https://doi.org/10.1038/msb.2010.109