Spatial distribution of cytoskeleton-mediated feedback controls cell polarization: A computational study.

In the social amoeba Dictyostelium, cell motility is regulated through a signal transduction excitable network that interfaces with the cytoskeleton to control actin polymerization patterns. In turn, the cytoskeleton influences the signaling machinery via several feedback loops, but the nature and f...

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Bibliographic Details
Published in:PLoS Computational Biology
Main Authors: Parijat Banerjee, Jonathan A Kuhn, Dhiman Sankar Pal, Yu Deng, Tatsat Banerjee, Peter N Devreotes, Pablo A Iglesias
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-10-01
Online Access:https://doi.org/10.1371/journal.pcbi.1013036