Effects of esketamine and fluoxetine on depression-like behaviors in chronic variable stress: a role of plasma inflammatory factors

Mounting evidence has identified the rapid and sustained antidepressive and anxiolytic-like effects of esketamine. However, the underlying mechanism of this no-monoamine target rapid-onset antidepressant is still underexplored. Immune-inflammatory pathways and cell-mediated immune activation, mainly...

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Bibliographic Details

Published in:	Frontiers in Psychiatry
Main Authors:	Haixia Chen, Xinxin Zhao, Xinxu Ma, Hongzhe Ma, Cuihong Zhou, Yunyun Zhang, Zhengwu Peng, Shanshan Xue, Min Cai
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-05-01
Subjects:	esketamine fluoxetine major depressive disorder chronic variable stress inflammatory cytokines
Online Access:	https://www.frontiersin.org/articles/10.3389/fpsyt.2024.1388946/full