Design Strategies and Precautions for Using Vaccinia Virus in Tumor Virotherapy

Oncolytic virotherapy has emerged as a novel form of cancer immunotherapy. Oncolytic viruses (OVs) can directly infect and lyse the tumor cells, and modulate the beneficial immune microenvironment. Vaccinia virus (VACV) is a promising oncolytic vector because of its high safety, easy gene editing, a...

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Bibliographic Details

Published in:	Vaccines
Main Authors:	Xinjun Liu, Jian Zhao, Xiaopeng Li, Fengxue Lao, Min Fang
Format:	Article
Language:	English
Published:	MDPI AG 2022-09-01
Subjects:	oncolytic virotherapy vaccinia virus tumor treatment personalized treatment
Online Access:	https://www.mdpi.com/2076-393X/10/9/1552