Dysregulation of Astrocytic Glutamine Transport in Acute Hyperammonemic Brain Edema
Acute liver failure (ALF) impairs ammonia clearance from blood, which gives rise to acute hyperammonemia and increased ammonia accumulation in the brain. Since in brain glutamine synthesis is the only route of ammonia detoxification, hyperammonemia is as a rule associated with increased brain glutam...
| Published in: | Frontiers in Neuroscience |
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| Main Authors: | , , |
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2022-06-01
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| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fnins.2022.874750/full |