In Vivo and In Silico Study of Photodynamic Necrosis Volume in Rat Liver

Photodynamic therapy is a treatment modality that can be used to treat various types of lesions. To produce cell death, reaching a certain threshold dose of reactive oxygen species (ROS) is required. The estimation of ROS production is of paramount importance to predict the depth of necrosis and to...

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Bibliographic Details
Published in:Photonics
Main Authors: Marlon Rodrigues Garcia, Víctor Sánchez, Thereza Cury Fortunato, Michelle Barreto Requena, Clóvis Grecco, José Dirceu Vollet-Filho, Layla Pires, Lilian Tan Moriyama, Sebastião Pratavieira
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Subjects:
photodynamic therapy (PDT)
mathematical model
PDT rate equations
Monte Carlo simulation
necrosis profile prediction
rat liver model
Online Access:https://www.mdpi.com/2304-6732/9/12/993

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https://www.mdpi.com/2304-6732/9/12/993

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