Glucocorticoid receptor-dependent induction of cripto-1 (one-eyed pinhead) inhibits zebrafish caudal fin regeneration

We previously used a chemical genetics approach with the larval zebrafish to identify small molecule inhibitors of tissue regeneration. This led to the discovery that glucocorticoids (GC) block early stages of tissue regeneration by the inappropriate activation of the glucocorticoid receptor (GR). W...

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Bibliographic Details

Published in:	Toxicology Reports
Main Authors:	Michael A. Garland, Sumitra Sengupta, Lijoy K. Mathew, Lisa Truong, Esther de Jong, Aldert H. Piersma, Jane La Du, Robert L. Tanguay
Format:	Article
Language:	English
Published:	Elsevier 2019-01-01
Online Access:	http://www.sciencedirect.com/science/article/pii/S2214750019300952