Lactylation and antitumor immunity

Lactylation, a recently discovered post-translational modification (PTM), plays a critical role in cancer biology. Warburg effect induces lactate accumulation, which serves as a metabolic end-product and intercellular signaling mediator within the tumor microenvironment (TME). Beyond fueling tumor g...

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書誌詳細

出版年:	Frontiers in Immunology
主要な著者:	Biao Yang, Lingyu Li, Dongmei Shi, Tao Zhong, Huabao Xiong
フォーマット:	論文
言語:	英語
出版事項:	Frontiers Media S.A. 2025-10-01
主題:	lactylation antitumor immunity lactate accumulation tumor microenvironment histone and non-histone lactylation immunosuppressive phenotypes
オンライン･アクセス:	https://www.frontiersin.org/articles/10.3389/fimmu.2025.1690068/full