YAP represses intestinal inflammation through epigenetic silencing of JMJD3

Abstract Background Epigenetics plays an important role in the pathogenesis of inflammatory bowel disease (IBD). Some studies have reported that YAP is involved in inflammatory response and can regulate target genes through epigenetic modifications. JMJD3, a histone H3K27me3 demethylase, is associat...

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Bibliographic Details
Published in:Clinical Epigenetics
Main Authors: Hua Zhu, Jiali Lu, MingYue Fu, Ping Chen, Yali Yu, Min Chen, Qiu Zhao, Min Wu, Mei Ye
Format: Article
Language:English
Published: BMC 2024-01-01
Subjects:
IBD
Hippo pathway
YAP
Histone modification
JMJD3
Online Access:https://doi.org/10.1186/s13148-024-01626-w

Internet

https://doi.org/10.1186/s13148-024-01626-w

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