Characterization of Three Variants of SARS-CoV-2 In Vivo Shows Host-Dependent Pathogenicity in Hamsters, While Not in K18-hACE2 Mice

Animal models are used in preclinical trials to test vaccines, antivirals, monoclonal antibodies, and immunomodulatory drug therapies against SARS-CoV-2. However, these drugs often do not produce equivalent results in human clinical trials. Here, we show how different animal models infected with som...

وصف كامل

التفاصيل البيبلوغرافية
الحاوية / القاعدة:Viruses
المؤلفون الرئيسيون: Gabriela Toomer, Whitney Burns, Liliana Garcia, Gerelyn Henry, Anthony Biancofiori, Albert George, Ciera Duffy, Justin Chu, Morgan Sides, Melissa Muñoz, Kelly Garcia, Anya Nikolai-Yogerst, Xinjian Peng, Landon Westfall, Robert Baker
التنسيق: مقال
اللغة:الإنجليزية
منشور في: MDPI AG 2022-11-01
الموضوعات:
SARS-CoV-2
COVID-19
animal models
Omicron B.1.1.529
Omicron BA5.2
Delta B.1.617.2
الوصول للمادة أونلاين:https://www.mdpi.com/1999-4915/14/11/2584

الانترنت

https://www.mdpi.com/1999-4915/14/11/2584

مواد مشابهة