Dependence on mitochondrial respiration of malignant T cells reveals a new therapeutic target for angioimmunoblastic T-cell lymphoma

Abstract Cancer metabolic reprogramming has been recognized as one of the cancer hallmarks that promote cell proliferation, survival, as well as therapeutic resistance. Up-to-date regulation of metabolism in T-cell lymphoma is poorly understood. In particular, for human angioimmunoblastic T-cell lym...

Full description

Bibliographic Details
Published in:Cell Death Discovery
Main Authors: Adrien Krug, Rana Mhaidly, Marie Tosolini, Laura Mondragon, Gamze Tari, Adriana Martinez Turtos, Rachel Paul-Bellon, Vahid Asnafi, Sandrine Marchetti, Léa Di Mascio, Marion Travert, Frédéric Bost, Emmanuel Bachy, Rafael J. Argüello, Jean-Jacques Fournié, Philippe Gaulard, François Lemonnier, Jean-Ehrland Ricci, Els Verhoeyen
Format: Article
Language:English
Published: Nature Publishing Group 2024-06-01
Online Access:https://doi.org/10.1038/s41420-024-02061-9