A novel synthetic oleanane triterpenoid, 2‐cyano‐3,12‐dioxoolean‐1,9‐dien‐28‐oic acid, regulates mechanical allodynia by rescuing neuronal cell death and glial cell activation in the spinal cord of resiniferatoxin‐treated rats

Abstract Background Treating postherpetic neuralgia (PHN), which is characterized with a long‐lasting lancinating mechanical allodynia or hyperalgesia, is a big challenge as it is hard to achieve complete resolution. A synthetic triterpenoid, CDDO (2‐cyano‐3,12‐dioxoolean‐1,9‐dien‐28‐oic acid) can e...

وصف كامل

التفاصيل البيبلوغرافية
الحاوية / القاعدة:	Brain and Behavior
المؤلفون الرئيسيون:	Ying‐Yi Lu, Chia‐Yang Lin, Hung‐Pei Tsai, Chih‐Lung Lin, Chieh‐Hsin Wu
التنسيق:	مقال
اللغة:	الإنجليزية
منشور في:	Wiley 2024-02-01
الموضوعات:	2‐cyano‐3,12‐dioxoolean‐1,9‐dien‐28‐oic acid mechanical allodynia resiniferatoxin triterpenoid
الوصول للمادة أونلاين:	https://doi.org/10.1002/brb3.3398

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