Exposure to oxLDL impairs TGF-β activity in human tendon cells

Abstract Background Previous studies have shown that patients with hypercholesterolemia experience elevated levels of oxidized LDL (oxLDL), a molecule which triggers inflammation and collagenase activity. In this study we discovered novel mechanistic effects of oxLDL on tendon cells and the mediator...

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Bibliographic Details
Published in:BMC Musculoskeletal Disorders
Main Authors: Rouhollah Mousavizadeh, Charlie M. Waugh, Erin DeBruin, Robert G. McCormack, Vincent Duronio, Alex Scott
Format: Article
Language:English
Published: BMC 2023-03-01
Subjects:
Tendon
oxLDL
TGF-β
Collagen matrix
Hyperlipidemia
Online Access:https://doi.org/10.1186/s12891-023-06308-x

Internet

https://doi.org/10.1186/s12891-023-06308-x

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